Immunization against Diphtheria with Alum-precipitated Toxoid--I
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چکیده
منابع مشابه
Studies on Tetanus Toxoid: III. Antitoxic Response in Guinea Pigs Immunized with Tetanus Alum-precipitated Toxoid Followed by Tetanus Spores.
When an individual has been given one or more injections of tetanus toxoid and, at a later date, is injured and possibly infected with Clostridium tetani, what further precautions should be taken: (1) Administer antitoxin? (2) Give another injection of tetanus toxoid to accelerate the production of antitoxin? (3) Give no further treatment, depending on his present immunity to take care of the i...
متن کاملProtection against group A streptococcus by immunization with J8-diphtheria toxoid: contribution of J8- and diphtheria toxoid-specific antibodies to protection.
A conformationally constrained, minimally conserved peptide from the M protein of group A streptococcus (GAS) has been defined. It consists of 12 amino acids from the C-repeat region within a non-M protein helix-forming sequence and is referred to as "J8." Here, we investigate the immunogenicity of a J8-diphtheria toxoid (DT) conjugate adjuvanted with the human-compatible adjuvants, SBAS2 and a...
متن کاملImmunogenicity of IRIV- versus alum-adjuvanted diphtheria and tetanus toxoid vaccines in influenza primed mice.
The immunogenicity and protectivity of two different toxoid vaccines were compared in mice. In one formulation, toxoids (diphtheria or tetanus) were adsorbed to alumoxid, whereas in the other formulation the toxoids were crosslinked to immunopotentiating reconstituted influenza virosomes (IRIVs). A preimmunization with influenza antigens is necessary for a good anti-toxoid antibody response whe...
متن کاملImmunization with Tetanus Toxoid
Although immunization with tetanus toxoid cannot be expected to produce an adequate permanent immunity, a number of investigators have confirmed and extended the observation of Ramon3 to the effect that an organism, once immunized, will respond to further injections of toxoid with an accelerated and increased antitoxin production. That this response to the "injection de rappel" does occur has b...
متن کاملCellobiose-coated poly (lactide-co-glycolide) particles loaded with diphtheria toxoid for per os immunization
AIM To evaluate the dose-dependent immunogenic properties of poly(lactide-co-glycolide) (PLGA) particles coated with cellobiose as antigen carriers for oral immunization. METHODS Two types of PLGA-cellobiose particles (PLGA-cellobiose-1, ~ 0.8 μm and PLGA-cellobiose-2, ~ 1.2 μm) containing non-toxic recombinant subunit B (SbB) of diphtheria toxin fused with enhanced green fluorescent protein ...
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ژورنال
عنوان ژورنال: BMJ
سال: 1942
ISSN: 0959-8138,1468-5833
DOI: 10.1136/bmj.1.4235.315